Alice M. Tang, Jane Lanzillotti, Kristy Hendricks, Jul Gerrior, Mayurika Ghosh, Margo Woods and Christine Wanke
AIDS 2005, 19:847–861
Malnutrition, often accompanied by low serum levels of micronutrients, was common in HIV-infection prior to the introduction of highly active antiretroviral therapy (HAART), and is still common in much of the world that has limited access to antiretroviral therapy (ART). Chronic diarrhea, anorexia, malabsorption, impaired nutrient storage, increased energy demands and altered metabolism were the primary contributors to these nutritional deficiencies. Today, macronutrient deficiencies are less common and less severe in HIV-infected populations living in resource-sufficient countries. However, following the introduction of HAART, new questions about the importance of micronutrients in HIV infection are emerging.